Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331019 | 0.91 | OPRM1 (0.50) | HTR2AOPRM1TMEM97 | |
| SCHEMBL5354436 | 0.90 | HTR2A (0.55) | HTR2AOPRM1TMEM97 | |
| SCHEMBL5353321 | 0.88 | OPRM1 (0.49) | HTR2AOPRM1TMEM97 | |
| SCHEMBL341090 | 0.87 | HTR2A (0.59) | HTR2AOPRM1TMEM97 | |
| SCHEMBL341115 | 0.85 | HTR2A (0.61) | HTR2AOPRM1TMEM97 | |
| Oxalic Acid SCHEMBL10321244 | 0.85 | HTR2A (0.57) | HTR2AOPRM1TMEM97 | |
| Hydrochloric Acid SCHEMBL10322168 | 0.84 | HTR2A (0.60) | HTR2AOPRM1TMEM97 | |
| SCHEMBL5471848 | 0.83 | OPRM1 (0.44) | HTR2AOPRM1TMEM97 | |
| SCHEMBL342314 | 0.82 | HTR2A (0.54) | HTR2AOPRM1 | |
| SCHEMBL342383 | 0.82 | HTR2A (0.79) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124136-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |