Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392779 | 0.93 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL332281 | 0.83 | KCNN4 (0.56) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL27685085 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL2279828 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL10915007 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL584588 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL5240188 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL4543871 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL8188378 | 0.71 | KMT2A (0.46) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 | |
| SCHEMBL1845371 | 0.71 | KMT2A (0.43) | CYP11B1CYP11B2KMT2AKCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |