Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868644 | 0.77 | CTSK (0.62) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL1868648 | 0.77 | CTSK (0.62) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL25348435 | 0.76 | CTSK (0.59) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL3611760 | 0.76 | CTSK (0.59) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL3611757 | 0.76 | CTSK (0.59) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL16119292 | 0.75 | CTSK (0.57) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL1424546 | 0.74 | CTSK (0.65) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL21427217 | 0.74 | CTSK (0.65) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL21119399 | 0.74 | CTSK (0.65) | CTSKCTSSAAK1CACNA1BHDAC4 | |
| SCHEMBL23118362 | 0.74 | CTSK (0.65) | CTSKCTSSAAK1CACNA1BHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | CTSK 3691/4885CTSS 1885/4885AAK1 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.