Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cycloserine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.79 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.79 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.79 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levcycloserine SCHEMBL19640318 | 1.00 | BLM (0.79) | BLMMEN1GRIN2DLMNACYP3A4 | |
| Cycloserine SCHEMBL34323 | 0.89 | — | — | |
| Cycloserine SCHEMBL18584681 | 0.89 | BLM (1.00) | BLMMEN1GRIN2DLMNACYP3A4 | |
| Cycloserine SCHEMBL34322 | 0.89 | — | — | |
| Cycloserine SCHEMBL8681114 | 0.89 | BLM (1.00) | BLMMEN1GRIN2DLMNACYP3A4 | |
| Levcycloserine SCHEMBL243772 | 0.89 | — | — | |
| Cycloserine SCHEMBL8681117 | 0.89 | BLM (1.00) | BLMMEN1GRIN2DLMNACYP3A4 | |
| Cycloserine SCHEMBL10448776 | 0.87 | — | — | |
| Cycloserine SCHEMBL6571320 | 0.87 | — | — | |
| Cycloserine SCHEMBL429258 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029817-B2 | Method for manufacturing water-in-oil-in-water multiple emulsion | FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE (TW) | 2024-07-09 | — | — | US | disclosed |
| US-11622569-B2 | Bacillus microbial terroir for pathogen control in swine | CHURCH & DWIGHT CO., INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11607434-B2 | Bacillus compositions and methods of use with ruminants | CHURCH & DWIGHT CO., INC. (US) | 2023-03-21 | — | — | US | disclosed |
| US-20220400695-A1 | PEANUT MILK PRODUCT WITH SUPERIOR PEANUT TASTE, AROMA AND TO IMPROVE GUT MICROBIOTA AND PREPARATION PROCESS AND USE THEREOF | AGV PRODUCTS CORP. (TW) | 2022-12-22 | — | — | US | disclosed |
| CN-111004740-B | Basic nutrient solution for rapidly stabilizing in-vitro intestinal flora and application thereof | 南方医科大学 | 2022-03-29 | — | — | CN | disclosed |
| US-20210393710-A1 | METHOD FOR MANUFACTURING WATER-IN-OIL-IN-WATER MULTIPLE EMUSION | FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE (TW) | 2021-12-23 | — | — | US | disclosed |
| US-20210077545-A1 | BACILLUS COMPOSITIONS AND METHODS OF USE WITH RUMINANTS | CHURCH & DWIGHT CO., INC. (US) | 2021-03-18 | — | — | US | disclosed |
| EP-3198275-B1 | STERILIZATION COMPOSITIONS AND METHODS | SPS MED SUPPLY CORP (US) | 2021-03-10 | — | — | EP | disclosed |
| CN-112294933-A | Powder for assisting in protecting gastric mucosa injury and adjusting intestinal flora and preparation method thereof | 无限极（中国）有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-10835561-B2 | Bacillus compositions and methods of use with ruminants | CHURCH & DWIGHT CO., INC. (US) | 2020-11-17 | — | — | US | disclosed |
| EP-3198275-A1 | STERILIZATION COMPOSITIONS AND METHODS | SPS Medical Supply Corp. (US) | 2017-08-02 | — | — | EP | disclosed |
| CN-106728077-A | Composition with regulating intestinal canal Bacterial community and the anti-effect that treats constipation and preparation method and application | 南京中医药大学 | 2017-05-31 | — | — | CN | disclosed |
| WO-2016049311-A1 | STERILIZATION COMPOSITIONS AND METHODS | SPS MEDICAL SUPPLY CORP. (US) | 2016-03-31 | — | — | WO | disclosed |
| CN-103343158-B | Detection paper piece for clostridium perfringens, preparation method and application for same | UNIV JILIN AGRICULTURAL | 2014-05-14 | — | — | CN | disclosed |
| CN-103343158-A | Detection paper piece for clostridium perfringens, preparation method and application for same | UNIV JILIN AGRICULTURAL | 2013-10-09 | — | — | CN | disclosed |
| US-8540981-B1 | Bacillus strains useful against calf pathogens and scours | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2013-09-24 | — | — | US | disclosed |
| US-20130032547-A1 | STABILIZATION AND DISINFECTION OF WASTES USING HIGH ENERGY E-BEAM AND CHEMICAL OXIDANTS | THE TEXAS A&M UNIVERSITY SYSTEM | 2013-02-07 | — | — | US | disclosed |
| US-7311934-B2 | Method of inhibiting the growth of Clostridium perfringens in meat products | WTI, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20050158432-A1 | Method of and composition for inhibiting the growth of Clostridium perfringens in meat products | WTI, INC. (US) | 2005-07-21 | — | — | US | disclosed |
| US-20030091706-A1 | Method of and composition for inhibiting the growth of clostridium perfringens in meat products | WTI, INC. | 2003-05-15 | — | — | US | disclosed |