Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cycloserine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloserine SCHEMBL34322 | 0.97 | — | — | |
| Cycloserine SCHEMBL18584681 | 0.97 | BLM (1.00) | — | |
| Cycloserine SCHEMBL8681117 | 0.97 | BLM (1.00) | — | |
| Levcycloserine SCHEMBL243772 | 0.97 | — | — | |
| Cycloserine SCHEMBL8681114 | 0.97 | BLM (1.00) | — | |
| Cycloserine SCHEMBL34323 | 0.97 | — | — | |
| Cycloserine SCHEMBL429258 | 0.95 | — | — | |
| Cycloserine SCHEMBL10448776 | 0.95 | — | — | |
| Levcycloserine SCHEMBL19640318 | 0.87 | BLM (0.79) | — | |
| Cycloserine SCHEMBL5351530 | 0.87 | BLM (0.79) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470106-A1 | METHOD OF MANUFACTURING AN AMORPHOUS FORM OF THE HEMI-CALCIUM SALT OF (3R, 5R) 7- 3-PHENYL-4-PHENYLCARBAMOYL-2-(4-FLUOROPHENYL)-5-ISOPROPYL-PYRROL-1-YL!-3, 5-DIHYDROXYHEPTANOIC ACID (ATORVASTATIN) | Zentiva, A.S. (CZ) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003068739-A1 | METHOD OF MANUFACTURING AN AMORPHOUS FORM OF THE HEMI-CALCIUM SALT OF (3R, 5R) 7- 3-PHENYL-4-PHENYLCARBAMOYL-2-(4-FLUOROPHENYL)-5-ISOPROPYL-PYRROL-1-YL!-3, 5-DIHYDROXYHEPTANOIC ACID (ATORVASTATIN) | ZENTIVA A.S. (CZ) | 2003-08-21 | — | — | WO | disclosed |