SCHEMBL5351752

SCHEMBL5351752

O=S(=O)(O)c1ccc(/N=N/c2c(O)c(S(=O)(=O)O)cc3cc(S(=O)(=O)O)ccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.68
CYP1A2 P05177 3/20 0.68
ALDH1A1 P00352 2/20 0.68
THRB P10828 2/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
CYP2C9 P11712 2/20 0.63
ENPP2 Q13822 7/20 0.60
CD40 P25942 1/20 0.55
CD40LG P29965 1/20 0.55
SUMO2 P61956 1/20 0.53
SUMO1 P63165 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP2 Q9HC62 1/20 0.53
TSHR P16473 1/20 0.48
PTPRA P18433 1/20 0.48
PTPRB P23467 1/20 0.48
CYP2C19 P33261 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351756 1.00 HIF1A (0.68) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL1259518 0.94 CYP1A2 (0.74) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL23259433 0.93 CYP1A2 (0.71) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL16691181 0.93 CYP1A2 (0.71) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL933794 0.93 CYP1A2 (0.71) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL17804082 0.92 CYP1A2 (0.76) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL26386 0.92 THRB (0.69) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL1598803 0.92 THRB (0.69) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL4659395 0.92 THRB (0.69) HIF1ACYP1A2ALDH1A1THRBMEN1
SCHEMBL28661864 0.91 THRB (0.67) HIF1ACYP1A2ALDH1A1THRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7306632-B2 Leave-in color conditioner HAIRMARKER LLC (US) 2007-12-11 US disclosed
US-20050198746-A1 Leave-in color conditioner HAIRMARKER LLC 2005-09-15 US disclosed