Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535138 | 0.98 | KDM4E (0.36) | KDM4EPOLBALDH1A1SMYD2CYP3A4 | |
| SCHEMBL535190 | 0.95 | KDM4E (0.34) | KDM4EPOLBALDH1A1SMYD2CYP3A4 | |
| SCHEMBL3856318 | 0.82 | DGAT1 (0.35) | KDM4EPOLBSMYD2CYP3A4HTT | |
| SCHEMBL8027742 | 0.82 | SMYD2 (0.33) | KDM4EPOLBSMYD2CYP3A4HTT | |
| SCHEMBL2955809 | 0.82 | SMYD2 (0.33) | KDM4EPOLBSMYD2CYP3A4HTT | |
| SCHEMBL17839089 | 0.79 | NR1H2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL17839109 | 0.79 | SMYD2 (0.34) | ALDH1A1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL18748478 | 0.79 | NR1H2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL30563707 | 0.78 | SMYD2 (0.36) | ALDH1A1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL8168666 | 0.78 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185518-B1 | Aryloxyacetamide derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-08 | — | — | EP | disclosed |