Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501939 | 0.97 | RAB9A (0.68) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL1306777 | 0.95 | RAB9A (0.71) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL29538889 | 0.95 | RAB9A (0.71) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL8502308 | 0.95 | RAB9A (0.71) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL5738053 | 0.94 | RAB9A (0.70) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL5738051 | 0.94 | RAB9A (0.70) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL8503121 | 0.93 | RAB9A (0.66) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL13645586 | 0.93 | RAB9A (0.68) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL31515434 | 0.92 | CYP2C9 (0.74) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL8503345 | 0.91 | RAB9A (0.64) | RAB9ANPC1CYP2C9CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007129328-A2 | PROCESS FOR PREPARING 2-[PYRIDINYL]SULFINYL-SUBSTITUTED BENZIMIDAZOLES | CADILA HEALTHCARE LIMITED (IN) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007129328-A2 | PROCESS FOR PREPARING 2-[PYRIDINYL]SULFINYL-SUBSTITUTED BENZIMIDAZOLES | CADILA HEALTHCARE LIMITED (IN) | 2007-11-15 | — | — | WO | disclosed |
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |