Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 4/20 | 0.33 |
| ▸ | MC5R | P33032 | 3/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845539 | 0.88 | ALDH1A1 (0.46) | HTR2CSRCPOLBMAPT | |
| SCHEMBL5344813 | 0.88 | ALDH1A1 (0.46) | HTR2CSRCPOLBMAPT | |
| Hydrochloric Acid SCHEMBL5363345 | 0.87 | ALDH1A1 (0.45) | HTR2CSRCPOLBMAPT | |
| Hydrochloric Acid SCHEMBL5343346 | 0.87 | ALDH1A1 (0.45) | HTR2CSRCPOLBMAPT | |
| SCHEMBL4842911 | 0.85 | EPHX1 (0.43) | HTR2CHTR2BGAAMAPT | |
| Hydrochloric Acid SCHEMBL5361556 | 0.85 | EPHX1 (0.43) | HTR2CHTR2BGAAMAPT | |
| SCHEMBL4843557 | 0.85 | CACNA1B (0.43) | MAPK14HTR2CHTR2BMAPK11SRC | |
| Hydrochloric Acid SCHEMBL4841873 | 0.84 | CACNA1B (0.43) | MAPK14HTR2CHTR2BMAPK11SRC | |
| SCHEMBL5356917 | 0.83 | MAPK14 (0.40) | MAPK14HTR2CHTR2BMAPK11GAA | |
| SCHEMBL5354944 | 0.83 | MAPK14 (0.35) | MAPK14HTR2CHTR2BMAPK11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | disclosed |