Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356903 | 0.88 | PTH1R (0.34) | PTH1R | |
| SCHEMBL5350284 | 0.87 | PTH1R (0.39) | PTH1RKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL5326300 | 0.79 | PTH1R (0.48) | PTH1R | |
| SCHEMBL5350400 | 0.70 | PTH1R (0.51) | PTH1R | |
| SCHEMBL5363678 | 0.69 | PTH1R (0.56) | PTH1R | |
| SCHEMBL5356818 | 0.69 | PTH1R (0.51) | PTH1R | |
| SCHEMBL5322907 | 0.68 | PTH1R (0.49) | PTH1R | |
| SCHEMBL5359561 | 0.67 | PTH1R (0.46) | PTH1R | |
| SCHEMBL5344822 | 0.66 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5360369 | 0.65 | PTH1R (0.49) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |