Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 11/20 | 0.88 |
| ▸ | BACE1 | P56817 | 15/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352739 | 1.00 | CTSD (0.88) | CTSDBACE1BCHECYP3A4 | |
| SCHEMBL3353823 | 0.94 | CTSD (1.00) | CTSDBACE1BCHECYP3A4 | |
| SCHEMBL3353827 | 0.94 | CTSD (1.00) | CTSDBACE1BCHECYP3A4 | |
| SCHEMBL6648504 | 0.89 | BACE1 (1.00) | CTSDBACE1BCHE | |
| SCHEMBL6648502 | 0.89 | BACE1 (1.00) | CTSDBACE1BCHE | |
| SCHEMBL3351820 | 0.86 | CTSD (0.74) | CTSDBACE1BCHE | |
| SCHEMBL3356621 | 0.86 | BACE1 (1.00) | CTSDBACE1BCHE | |
| SCHEMBL3351811 | 0.86 | CTSD (0.74) | CTSDBACE1BCHE | |
| SCHEMBL3356623 | 0.86 | BACE1 (1.00) | CTSDBACE1BCHE | |
| SCHEMBL3350015 | 0.86 | BACE1 (0.75) | CTSDBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC | 2007-09-13 | — | — | US | claimed |
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | claimed |
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PHARMACIA & UPJOHN COMPANY | 2002-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PSEN2, PSEN1, APP | CTSD 2080/4885BACE1 4/4885BCHE 12/4885 |
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, CHAT | CTSD 1351/4885BACE1 7/4885BCHE 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.