Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535276 | 1.00 | F10 (0.33) | F10MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10170456 | 0.92 | F10 (0.34) | F10MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL408556 | 0.92 | F10 (0.34) | F10MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL408557 | 0.92 | F10 (0.34) | F10MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL408854 | 0.81 | SLC6A2 (0.37) | F10MAPTALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL9968914 | 0.81 | MTNR1A (0.36) | F10MAPTKDM4EALDH1A1PARP1 | |
| SCHEMBL2772719 | 0.81 | MTNR1A (0.36) | F10MAPTKDM4EALDH1A1PARP1 | |
| SCHEMBL2772718 | 0.81 | MTNR1A (0.36) | F10MAPTKDM4EALDH1A1PARP1 | |
| SCHEMBL10170444 | 0.81 | SLC6A2 (0.37) | F10MAPTALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL408853 | 0.81 | SLC6A2 (0.37) | F10MAPTALDH1A1SMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-A2 | OXADIAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-02-08 | — | — | EP | disclosed |
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115751-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010112461-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-07 | — | — | WO | disclosed |