SCHEMBL5352787

SCHEMBL5352787

COC(=O)C(=O)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TET2 Q6N021 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
TSHR P16473 3/20 0.39
HCAR2 Q8TDS4 2/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
NFKB1 P19838 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TGFBR1 P36897 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8832445 0.92 ALDH1A1 (0.50) ALDH1A1TET2EGLN1TSHRHCAR2
Ethylene Glycol SCHEMBL27904942 0.89 ALDH1A1 (0.43) ALDH1A1TET2EGLN1TSHRHCAR2
SCHEMBL6950834 0.82 ALDH1A1 (0.56) ALDH1A1TET2EGLN1TSHRHCAR2
SCHEMBL8295 0.82
SCHEMBL5269839 0.82
SCHEMBL27549795 0.82
SCHEMBL28267249 0.80 GAA (0.48) ALDH1A1EGLN1TSHRHSD17B10MGAM
SCHEMBL23640544 0.79 ALDH1A1 (0.41) ALDH1A1TET2EGLN1TSHRHCAR2
SCHEMBL28345369 0.78
Ammonia Solution, Strong SCHEMBL11801654 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102898304-B Method for recovering dimethyl oxalate in preparation process of ethylene glycol from synthetic gas ANHUI HUAIHUA CHEMICAL GROUP 2014-09-10 CN claimed
CN-101993366-B Method for preparing oxalate by using CO gaseous phase process CHINA PETROLEUM & CHEMICAL 2014-01-22 CN claimed
CN-103467290-A Method and apparatus for preparing dimethyl oxalate in process of preparing ethylene glycol from synthesis gas ANHUI HUAIHUA CHEMICAL GROUP 2013-12-25 CN claimed
CN-101830776-B Method for synthesizing ethanol UNIV ZHEJIANG 2013-09-25 CN claimed
CN-102219680-B Method for preparing oxalic ester by CO gas-phase process CHINA PETROLEUM & CHEMICAL 2013-09-18 CN claimed
CN-102964248-A Method for producing nitric oxide and synthesizing dimethyl oxalate through carbonylation JIUTAI ENERGY TECHNOLOGY CO LTD 2013-03-13 CN claimed
CN-102911046-A Dimethyl oxalate purification method during CO coupling dimethyl oxalate synthesis process CHINA PETROLEUM & CHEMICAL 2013-02-06 CN claimed
CN-102898304-A Method for recovering dimethyl oxalate in preparation process of ethylene glycol from synthetic gas ANHUI HUAIHUA CHEMICAL GROUP 2013-01-30 CN claimed
CN-202322670-U Anti-curing device system for dimethyl oxalate in industrial production of glycol ANHUI HUAIHUA CHEMICAL GROUP 2012-07-11 CN claimed
CN-102516031-A Method and device system for preventing DMO (dimethyl oxalate) from curing in ethylene glycol industrial production ANHUI HUAIHUA CHEMICAL GROUP 2012-06-27 CN claimed
CN-102442903-A Method for recovering dimethyloxalate and dimethyl carbonate in waste gas during commercial glycol production ANHUI HUAI AN CHEMICAL GROUP 2012-05-09 CN claimed
CN-102219680-A Method for preparing oxalic ester by CO gas-phase process CHINA PETROLEUM & CHEMICAL 2011-10-19 CN claimed
CN-101993366-A Method for preparing oxalate by using CO gaseous phase process CHINA PETROLEUM & CHEMICAL 2011-03-30 CN claimed
EP-0922046-B1 PROCESS FOR THE PREPARATION OF 7-ALKOXYALKYL-1,2,4-TRIAZOLO 1,5-A] PYRIMIDINE DERIVATIVES ABBOTT GMBH & CO KG (DE) 2004-04-28 EP claimed
CN-1080265-C Process for preparing 7-alkoxyalkyl-1, 2, 4-triazolo [1, 5-a ] pyrimidine derivatives KNOLL AG (DE) 2002-03-06 CN claimed
CN-1228093-A Process for preparing 7-alkoxyalkyl-1, 2, 4-triazolo [1, 5-a ] pyrimidine derivatives KNOLL AG (DE) 1999-09-08 CN claimed
CN-113717102-B New preparation method of isoquinoline compound 南通常佑药业科技有限公司 2024-07-26 CN disclosed
CN-117337288-A AXL inhibitor compounds 艾库斯生物科学有限公司 2024-01-02 CN disclosed
EP-0743938-A1 SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-11-27 EP disclosed
WO-1995021817-A1 SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-08-17 WO disclosed