SCHEMBL5352805

SCHEMBL5352805

CC(C)(C)c1ccc(CC(c2ccc(C(C)(C)C)c3c2Cc2ccccc2-3)[Zr](Cl)Cl)c2c1-c1ccccc1C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5363318 0.85 PNMT (0.34)
SCHEMBL5351377 0.83 MAP3K9 (0.30)
SCHEMBL6347029 0.76 MAP3K9 (0.32)
Hydrochloric Acid SCHEMBL5351379 0.75 MAP3K9 (0.39)
Hydrochloric Acid SCHEMBL5352807 0.75 MAP3K9 (0.39)
SCHEMBL5348067 0.73 PNMT (0.51)
SCHEMBL3828187 0.73 PNMT (0.35)
SCHEMBL9171570 0.72 MAP3K9 (0.39)
SCHEMBL8857105 0.72 MAP3K9 (0.34)
SCHEMBL5352093 0.71 MAP3K9 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed
EP-0524624-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1993-01-27 EP claimed
US-7230128-B2 Organometallic fluorenyl compounds, preparations, and use PHILLIPS POTROLEUM COMPANY (US) 2007-06-12 US disclosed
US-20060122344-A1 Organometallic Fluorenyl Compounds, Preparations, and Use PHILLIPS PETROLEUM COMPANY (US) 2006-06-08 US disclosed
US-6420579-B1 SILYL, GERMANIUM OR TIN RADICALS WITH TITANIUM, ZIRCONIUM, HAFNIUM, VANADIUM, NIOBIUM AND TANTALUM METALS PHILLIPS PETROLEUM COMPANY 2002-07-16 US disclosed
US-6403734-B1 POLYMERIZING ALPHA-OLEFIN BY CONTACTING WITH CATALYST SYSTEM COMPRISING BRIDGED FLUORENYL METALLOCENE CONTAINING METAL OF GROUP 4 OR 5 AND SUITABLE COCATALYST PHILLIPS PETROLEUM COMPANY 2002-06-11 US disclosed
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP disclosed
US-6162936-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2000-12-19 US disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 EP disclosed
US-5436305-A Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent PHILLIPS PETROLEUM COMPANY (US) 1995-07-25 US disclosed
EP-0524624-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1993-01-27 EP disclosed