Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.74 |
| ▸ | MEN1 | O00255 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | GAA | P10253 | 6/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | GFER | P55789 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244894 | 0.85 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1507639 | 0.82 | ALDH1A1 (0.59) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL15217657 | 0.79 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1GAA | |
| Sivifene SCHEMBL18821 | 0.79 | KMT2A (0.72) | MAPTKMT2AMEN1ALDH1A1GAA | |
| Sivifene SCHEMBL29386100 | 0.79 | KMT2A (0.72) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL13576573 | 0.78 | MAPT (0.88) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4221657 | 0.76 | HPGD (0.68) | MAPTKMT2AMEN1ALDH1A1GAA | |
| P-Nitrophenol SCHEMBL11048842 | 0.75 | CES1 (0.58) | MAPTKMT2AMEN1ALDH1A1GAA | |
| P-Nitrophenol SCHEMBL29806213 | 0.75 | CES1 (0.58) | MAPTKMT2AMEN1ALDH1A1GAA | |
| P-Nitrophenol SCHEMBL1839 | 0.75 | CES1 (0.58) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105827-A1 | Estrogen receptor modulators | BLIZZARD TIMOTHY A | 2007-05-10 | — | — | US | disclosed |
| EP-0187039-B1 | ANTIESTROGENIC HYDRAZONES | Morgan, Lee Roy (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4732904-A | ANTITUMOR AGENTS | MORGAN LEE R (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0187039-A1 | Antiestrogenic hydrazones | Morgan, Lee Roy (US) | 1986-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105827-A1 | Estrogen receptor modulators | ESR2, ESR1, GPER1 | MAPT 179/4885KMT2A 2570/4885MEN1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.