Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364985 | 0.91 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL3355061 | 0.85 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL5368557 | 0.76 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL3352374 | 0.74 | TLR7 (0.33) | TLR7 | |
| SCHEMBL8113805 | 0.74 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL14344867 | 0.74 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL5351611 | 0.74 | TLR7 (0.37) | TLR7TLR8 | |
| SCHEMBL5118920 | 0.72 | TLR7 (0.42) | TLR7TLR8 | |
| SCHEMBL3353979 | 0.72 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL3352028 | 0.72 | TLR7 (0.49) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143526-A2 | SUBSTITUTED TETRAHYDROIMIDAZONAPHTHYRIDINES AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-12-13 | — | — | WO | disclosed |