Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845886 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL8179839 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL7561421 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL11116040 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL15153587 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL7614472 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL686971 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL5353579 | 1.00 | GPR84 (0.45) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL686346 | 0.98 | — | — | |
| SCHEMBL7699865 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-113574041-A | Method for producing bisphenol and method for producing polycarbonate resin | 三菱化学株式会社 | 2021-10-29 | — | — | CN | disclosed |
| WO-2020189201-A1 | METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN | 三菱ケミカル株式会社 | 2020-09-24 | — | — | WO | disclosed |
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | WUXI APPTEC CO., LTD (CN) | 2018-11-15 | — | — | US | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| WO-2007093765-A1 | PROCESS FOR THE CYANATION OF ALDEHYDES | NPIL PHARMACEUTICALS (UK) LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
| EP-0807120-B1 | RUTHENIUM HYDROGENATION CATALYSTS | DU PONT (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0807098-B1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | DU PONT (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5741955-A | TRANSITION METAL COMPLEX CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0807098-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0807120-A1 | RUTHENIUM HYDROGENATION CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5689003-A | CATALYTIC HYDROGENATION OF NITRILES TO FORM AMINES WITH COMPLEXES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| US-5554778-A | IMINATION, REDUCTIVE HYDROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| WO-1996023753-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
| WO-1996023803-A1 | RUTHENIUM HYDROGENATION CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
| US-4904812-A | Preparation of unsaturated nitriles | BASF AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4085275-A | Production of di-unsaturated carboxylic acids | MONSANTO COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | GPR84 3979/4885SPHK1 2282/4885FFAR1 4119/4885 |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | GPR84 3979/4885SPHK1 2282/4885FFAR1 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.