Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.68 |
| ▸ | GNG2 | P59768 | 2/20 | 0.68 |
| ▸ | GNB1 | P62873 | 2/20 | 0.68 |
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237103 | 0.96 | MMP9 (0.64) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3236207 | 0.92 | OPRL1 (0.60) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3242010 | 0.91 | PLAU (0.58) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3245122 | 0.91 | MMP9 (0.58) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3244101 | 0.89 | MMP9 (0.57) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3240209 | 0.89 | MMP9 (0.60) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3231124 | 0.89 | PRKCI (0.59) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3236262 | 0.89 | MMP9 (0.63) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL5848272 | 0.88 | MMP9 (0.71) | MMP9GNG2GNB1MMP1MEN1 | |
| SCHEMBL3239642 | 0.88 | MMP9 (0.59) | MMP9GNG2GNB1MMP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235558-B2 | Inhibitors of the GPIb—vWF interaction, their preparation and use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | claimed |
| US-7235558-B2 | Inhibitors of the GPIb—vWF interaction, their preparation and use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |