SCHEMBL535480

SCHEMBL535480

CC=NNC(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19133302 0.81 LMNA (0.56)
SCHEMBL12680108 0.78 KDM4E (0.44)
SCHEMBL16659212 0.77
SCHEMBL14196325 0.77
SCHEMBL2943324 0.77 MIF (0.53)
SCHEMBL2943326 0.77 MIF (0.53)
SCHEMBL19133312 0.75 LMNA (0.50)
SCHEMBL19157188 0.75 LMNA (0.50)
SCHEMBL2607934 0.73 KDM4E (0.44)
SCHEMBL3173673 0.73 LMNA (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180215729-A1 NK 1 ANTAGONISTS OPKO HEALTH, INC. 2018-08-02 US disclosed
US-9969711-B2 NK1 antagonists OPKO HEALTH, INC. (US) 2018-05-15 US disclosed
US-20170029403-A1 NK 1 ANTAGONISTS OPKO HEALTH, INC. 2017-02-02 US disclosed
US-20170029403-A1 NK 1 ANTAGONISTS OPKO HEALTH, INC. 2017-02-02 US disclosed
US-9469629-B2 NK1 antagonists OPKO HEALTH, INC. (US) 2016-10-18 US disclosed
US-20140296196-A1 NK1 ANTAGONISTS OPKO HEALTH, INC. 2014-10-02 US disclosed
US-8785646-B2 Process for producing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
US-8754216-B2 NK1 antagonists OPKO HEALTH, INC. (US) 2014-06-17 US disclosed
US-8754216-B2 NK1 antagonists OPKO HEALTH, INC. (US) 2014-06-17 US disclosed
US-8541613-B2 Process for producing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-24 US disclosed
US-20100137362-A1 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137362-A1 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100120866-A1 PROCESS FOR PRODUCING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-05-13 US disclosed
US-20100113794-A1 METHOD FOR PRODUCING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-05-06 US disclosed
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
EP-2142530-A2 PROCESS FOR PRODUCING PESTICIDAL BENZAMIDE COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2010-01-13 EP disclosed
EP-2143720-A1 METHOD FOR PRODUCING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-01-13 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
WO-2008126933-A2 PROCESS FOR PRODUCING PESTICIDAL BENZAMIDE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed