SCHEMBL5354970

SCHEMBL5354970

COc1cc(N)c(OC)c2c(C)cc(O)nc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
TUBB4A P04350 2/20 0.35
TUBB P07437 2/20 0.35
TUBA3C P0DPH7 2/20 0.35
TUBA1B P68363 2/20 0.35
TUBA4A P68366 2/20 0.35
TUBB4B P68371 2/20 0.35
TUBB3 Q13509 2/20 0.35
TUBB2A Q13885 2/20 0.35
TUBB8 Q3ZCM7 2/20 0.35
TUBA3E Q6PEY2 2/20 0.35
TUBA1A Q71U36 2/20 0.35
TUBA1C Q9BQE3 2/20 0.35
TUBB6 Q9BUF5 2/20 0.35
TUBB2B Q9BVA1 2/20 0.35
TUBB1 Q9H4B7 2/20 0.35
CYP3A4 P08684 2/20 0.35
FYN P06241 1/20 0.35
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5362078 0.83 MAPT (0.41) MAPTCYP3A4JAK2JAK1TYK2
SCHEMBL11543061 0.73 MAPT (0.54) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL6227334 0.72 KDM4E (0.44) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5357984 0.71 HTT (0.38) MAPTCYP3A4FYNKDRAURKB
SCHEMBL8703095 0.71 GAA (0.36) MAPTCYP3A4JAK2JAK1TYK2
SCHEMBL12209739 0.69 MAPT (0.53) MAPTCYP3A4KDM4EALDH1A1
SCHEMBL4729404 0.69 CYP19A1 (0.38) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5359895 0.68 CD44 (0.38) MAPTNQO2KDM4EALDH1A1
SCHEMBL12192909 0.68 POLB (0.38) MAPTCYP3A4FYNDHFRKDM4E
SCHEMBL9123145 0.67 CYP3A4 (0.43) MAPTTUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
CN-1305971-C Method for producing disazo pigments CLARIANT GMBH (DE) 2007-03-21 CN disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
CN-1662610-A Method for producing disazo pigments CLARIANT GMBH (DE) 2005-08-31 CN disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 MAPT 1879/4885TUBB4A 623/4885TUBB 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.