Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228230 | 0.96 | THRB (0.56) | THRBHDAC1HDAC6 | |
| SCHEMBL8230284 | 0.93 | THRB (0.56) | THRBHDAC1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8229534 | 0.88 | THRB (0.68) | THRBHDAC1HDAC6 | |
| SCHEMBL8228589 | 0.87 | THRB (0.75) | THRBHDAC1HDAC6 | |
| SCHEMBL8220867 | 0.86 | THRB (0.61) | THRB | |
| SCHEMBL8225984 | 0.86 | THRB (0.69) | THRBHDAC1HDAC6 | |
| SCHEMBL5356583 | 0.86 | THRB (0.60) | THRB | |
| SCHEMBL8228557 | 0.85 | THRB (0.58) | THRBHDAC1HDAC6 | |
| SCHEMBL8225187 | 0.84 | THRB (0.59) | THRBHDAC1HDAC6 | |
| SCHEMBL8228162 | 0.84 | THRB (0.57) | THRBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |