SCHEMBL5355264

SCHEMBL5355264

CCCc1ncc(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.62
AGTR2 P50052 2/20 0.62
AGT P01019 2/20 0.47
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1970464 0.95 AGTR1 (0.56) AGTR1AGTR2AGT
SCHEMBL9455402 0.86 AGTR1 (0.59) AGTR1AGTR2AGTPPARG
SCHEMBL14855527 0.84 AGTR1 (0.66) AGTR1AGTR2AGT
SCHEMBL7308543 0.83 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL9026501 0.83 AGTR1 (0.54) AGTR1AGTR2AGT
SCHEMBL7301221 0.83 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL7400468 0.83 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL7304474 0.83 AGTR1 (0.64) AGTR1AGTR2AGT
SCHEMBL8252592 0.82 AGTR1 (0.55) AGTR1AGTR2AGT
SCHEMBL27405890 0.82 AGTR1 (0.49) AGTR1AGTR2AGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007148344-A2 PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL MATRIX LABORATORIES LIMITED (IN) 2007-12-27 WO disclosed