Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.65 |
| ▸ | HTR2C | P28335 | 5/20 | 0.65 |
| ▸ | HTR2B | P41595 | 5/20 | 0.65 |
| ▸ | HRH2 | P25021 | 9/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358193 | 0.91 | HTR2A (0.77) | HTR2AHTR2CHTR2BHRH2PKM | |
| SCHEMBL7094542 | 0.88 | HRH2 (0.60) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL5343881 | 0.88 | HRH2 (0.78) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL5343753 | 0.87 | HRH2 (0.58) | HTR2AHTR2CHTR2BHRH2PKM | |
| SCHEMBL5344193 | 0.87 | HRH2 (0.77) | HTR2AHTR2CHTR2BHRH2PKM | |
| SCHEMBL5345903 | 0.87 | HRH2 (0.60) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL4055550 | 0.86 | HTR2A (0.63) | HTR2AHTR2CHTR2BHRH2PKM | |
| SCHEMBL5355408 | 0.86 | HRH2 (0.84) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL4057396 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHRH2PKM | |
| SCHEMBL5358714 | 0.84 | HRH2 (0.80) | HTR2AHTR2CHTR2BHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189741-B2 | Indolylpiperidine derivatives as antihistaminic and antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2007-03-13 | — | — | US | claimed |
| EP-1330453-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-03-29 | — | — | EP | claimed |
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | claimed |
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | claimed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | claimed |
| US-7189741-B2 | Indolylpiperidine derivatives as antihistaminic and antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2007-03-13 | — | — | US | disclosed |
| EP-1330453-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2006-03-29 | — | — | EP | disclosed |
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | disclosed |
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | disclosed |