Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 9/20 | 0.60 |
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | HTR2C | P28335 | 7/20 | 0.52 |
| ▸ | HTR2B | P41595 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345903 | 0.88 | HRH2 (0.60) | HRH2HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL5355277 | 0.88 | HTR2A (0.65) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5343753 | 0.87 | HRH2 (0.58) | HRH2HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL5358714 | 0.87 | HRH2 (0.80) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5343881 | 0.84 | HRH2 (0.78) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5357911 | 0.79 | TSHR (0.54) | HRH2HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL5358193 | 0.79 | HTR2A (0.77) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5344193 | 0.76 | HRH2 (0.77) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5350942 | 0.76 | HTR6 (0.46) | HRH2HTR2AHTR2CHTR2BPOLB | |
| SCHEMBL5352014 | 0.75 | HTR2A (0.85) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | disclosed |