Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599267 | 0.81 | HCAR2 (0.56) | HCAR2POLBRAB9ANPC1KMT2A | |
| SCHEMBL2213943 | 0.81 | HCAR2 (0.56) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL8053528 | 0.78 | MAPK1 (0.62) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL163583 | 0.77 | MAPK1 (0.67) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL4490261 | 0.77 | MAPK1 (0.67) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL68056 | 0.77 | MAPK1 (1.00) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL3624738 | 0.77 | MAPK1 (0.67) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL21810960 | 0.76 | HCAR2 (1.00) | HCAR2MEN1KMT2A | |
| SCHEMBL23013382 | 0.76 | MAPK1 (0.65) | MAPK1HCAR2POLBRAB9ANPC1 | |
| SCHEMBL1009738 | 0.76 | MAPK1 (0.65) | MAPK1HCAR2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |