Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358351 | 0.84 | MAPK1 (0.61) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL13369577 | 0.83 | NPSR1 (0.52) | MAPK1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL23013382 | 0.79 | MAPK1 (0.65) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL18236174 | 0.79 | ALPL (0.41) | MAPK1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14019194 | 0.78 | MAPK1 (0.54) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL5355569 | 0.78 | MAPK1 (0.62) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL3624738 | 0.77 | MAPK1 (0.67) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL68056 | 0.77 | MAPK1 (1.00) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL163583 | 0.77 | MAPK1 (0.67) | MAPK1POLBRAB9ANPC1MEN1 | |
| SCHEMBL4490261 | 0.77 | MAPK1 (0.67) | MAPK1POLBRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114358-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |