SCHEMBL5355672

SCHEMBL5355672

Nc1nccc(C(=O)O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.57
MMP2 P08253 1/20 0.48
KDM4E B2RXH2 9/20 0.47
ALDH1A1 P00352 6/20 0.47
MAPT P10636 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
KDM4A O75164 2/20 0.47
MEN1 O00255 2/20 0.47
THRB P10828 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4C Q9H3R0 2/20 0.47
KDM6B O15054 1/20 0.47
KDM4D Q6B0I6 1/20 0.47
ASPH Q12797 1/20 0.46
KDM8 Q8N371 1/20 0.46
RAB9A P51151 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
HIF1AN Q9NWT6 1/20 0.44
SELL P14151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18226305 0.81 NAPRT (0.59) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL19857454 0.79 NAPRT (0.57) NAPRTKDM4EALDH1A1MAPTL3MBTL1
Hydrochloric Acid SCHEMBL18226370 0.79 NAPRT (0.57) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL245080 0.78 KDM4E (0.48) NAPRTMMP2KDM4EALDH1A1MAPT
SCHEMBL480040 0.78 NAPRT (0.55) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL2905936 0.78 NAPRT (0.55) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL28717057 0.78 KDM4E (0.63) NAPRTKDM4EALDH1A1MAPTL3MBTL1
SCHEMBL19857460 0.77 KDM4E (0.62) KDM4EALDH1A1MAPTL3MBTL1TDP1
SCHEMBL28361885 0.75 NAPRT (0.57) NAPRTMMP2KDM4EALDH1A1MAPT
SCHEMBL2221901 0.75 KDM4E (0.48) MMP2KDM4EALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-7160978-B2 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-09 US disclosed
US-7160978-B2 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-09 US disclosed
US-20040171756-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W (US) 2004-09-02 US disclosed