Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | F13A1 | P00488 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA6 | P23280 | 2/20 | 0.65 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | THPO | P40225 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.65 |
| ▸ | CASP2 | P42575 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermine SCHEMBL7750968 | 0.87 | CA12 (0.68) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL12482806 | 0.86 | CA12 (0.59) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL12482919 | 0.83 | PAOX (0.55) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL6536558 | 0.83 | MAOA (0.72) | CA12F13A1CA2CYP1A2ALOX15 | |
| Spermidine SCHEMBL2076472 | 0.83 | PAOX (0.67) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL30571402 | 0.83 | PAOX (0.55) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL3227990 | 0.81 | PAOX (0.53) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL6536854 | 0.81 | MAOA (0.69) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL18342530 | 0.81 | MAOA (0.69) | CA12F13A1CA2CYP1A2ALOX15 | |
| Succinamide SCHEMBL6536724 | 0.81 | MAOA (0.69) | CA12F13A1CA2CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208528-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |