Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GNG2 | P59768 | 2/20 | 0.53 |
| ▸ | GNB1 | P62873 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763069 | 0.80 | GNG2 (0.81) | MEN1KMT2AGNG2GNB1MMP1 | |
| SCHEMBL4825985 | 0.79 | DHODH (0.52) | MCHR1MEN1KMT2AGNG2GNB1 | |
| SCHEMBL4258680 | 0.77 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL13697268 | 0.76 | KMT2A (0.61) | MEN1KMT2AGNG2GNB1MMP1 | |
| SCHEMBL4816102 | 0.74 | POLB (0.43) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6199601 | 0.74 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL6204610 | 0.74 | MCHR1 (0.78) | MCHR1 | |
| SCHEMBL6203289 | 0.74 | MCHR1 (0.78) | MCHR1 | |
| SCHEMBL6203293 | 0.74 | MCHR1 (0.78) | MCHR1 | |
| SCHEMBL6204617 | 0.74 | MCHR1 (0.78) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189714-B2 | N-type calcium channel antagonists for the treatment of pain | ASTRAZENECA AB (SE) | 2007-03-13 | — | — | US | disclosed |