Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19022524 | 0.75 | ALDH1A1 (0.56) | ALDH1A1TDP1ADORA1KMT2AMGAM | |
| SCHEMBL7020065 | 0.74 | NPC1 (0.53) | ALDH1A1TDP1ADORA1KMT2AMAPT | |
| SCHEMBL31069690 | 0.74 | NPC1 (0.53) | ALDH1A1TDP1ADORA1KMT2AMAPT | |
| SCHEMBL650219 | 0.72 | GRIA1 (0.47) | ALDH1A1TDP1MAOBMAPTCYP3A4 | |
| SCHEMBL15413780 | 0.72 | QPCT (0.49) | ALDH1A1TDP1ADORA1KMT2AMAOB | |
| SCHEMBL15055251 | 0.72 | ALDH1A1 (0.66) | ALDH1A1TDP1ADORA1MAOBMGAM | |
| SCHEMBL17420850 | 0.72 | ALDH1A1 (0.66) | ALDH1A1TDP1ADORA1KMT2AMAOB | |
| SCHEMBL29021111 | 0.72 | ALDH1A1 (0.66) | ALDH1A1TDP1ADORA1KMT2AMAOB | |
| SCHEMBL5365772 | 0.71 | PTPRC (0.47) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL15477943 | 0.71 | ALDH1A1 (0.51) | ALDH1A1TDP1ADORA1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288564-B2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 2007-10-30 | — | — | US | disclosed |