Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.69 |
| ▸ | HEXB | P07686 | 6/20 | 0.69 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632858 | 1.00 | HEXA (0.69) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL8879310 | 0.98 | HEXA (0.71) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL8879380 | 0.93 | HEXA (0.71) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625395 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625535 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625518 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9625779 | 0.92 | HEXA (0.81) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL9626265 | 0.90 | HEXA (0.83) | HEXAHEXBSIRT1CYP3A4NFKB1 | |
| SCHEMBL24991893 | 0.88 | HPGD (0.60) | HEXAHEXBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10396736 | 0.86 | HEXA (0.69) | HEXAHEXBSIRT1CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180189460-A1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | UNIV TENNESSEE RES FOUND (US) | 2018-07-05 | — | — | US | disclosed |
| EP-2887939-B1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | UNIV TENNESSEE RES FOUND (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-2887939-A1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | University of Tennessee Research Foundation (US) | 2015-07-01 | — | — | EP | disclosed |
| US-9056835-B2 | LPA2 receptor-specific benzoic acid derivatives | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-06-16 | — | — | US | disclosed |
| US-20140206714-A1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2014036038-A1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-03-06 | — | — | WO | disclosed |
| US-20140057936-A1 | LPA2 Receptor-Specific Benzoic Acid Derivatives | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2013001498-A1 | AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2013-01-03 | — | — | WO | disclosed |
| US-20070027138-A1 | Derivatives and analogs of galanthamine | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT | 2007-02-01 | — | — | US | disclosed |
| US-20070027138-A1 | Derivatives and analogs of galanthamine | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT | 2007-02-01 | — | — | US | disclosed |
| EP-1181294-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | Sanochemia Pharmazeutika Aktiengesellschaft (AT) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001074820-A1 | NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN | SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) | 2001-10-11 | — | — | WO | disclosed |
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |
| US-3996363-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3959286-A | ANTIDEPRESSANTS, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-05-25 | — | — | US | disclosed |
| US-3947452-A | ANTIDEPRESSANT, ANTIANXIETY, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-03-30 | — | — | US | disclosed |
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |
| US-3940398-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140057936-A1 | LPA2 Receptor-Specific Benzoic Acid Derivatives | LPAR2, LPAR1, LPAR3 | HEXA 3799/4885HEXB 3868/4885SIRT1 1606/4885 |
| US-20070027138-A1 | Derivatives and analogs of galanthamine | GALR2, GALR1, GALR3 | HEXA 112/4885HEXB 198/4885SIRT1 585/4885 |
| US-20140206714-A1 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES | LPAR2, LPAR1, LPAR4 | HEXA 3636/4885HEXB 3780/4885SIRT1 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.