SCHEMBL9625535

SCHEMBL9625535

O=C1c2cccc3cccc(c23)C(=O)N1CCCCCCCCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 6/20 0.81
HEXB P07686 6/20 0.81
SIRT1 Q96EB6 3/20 0.73
CYP3A4 P08684 1/20 0.71
NFKB1 P19838 1/20 0.71
HSD17B10 Q99714 1/20 0.71
KMT2A Q03164 3/20 0.71
MEN1 O00255 2/20 0.71
POLB P06746 2/20 0.71
NR1I2 O75469 1/20 0.71
AHR P35869 1/20 0.71
RAD52 P43351 1/20 0.71
RCE1 Q9Y256 1/20 0.71
ALDH1A1 P00352 4/20 0.70
HDAC3 O15379 1/20 0.70
LTA4H P09960 1/20 0.70
HDAC4 P56524 1/20 0.70
HDAC1 Q13547 1/20 0.70
HDAC7 Q8WUI4 1/20 0.70
HDAC2 Q92769 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625518 1.00 HEXA (0.81) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9625779 1.00 HEXA (0.81) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9625395 1.00 HEXA (0.81) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9626265 0.98 HEXA (0.83) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL1657181 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9625427 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9627022 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL20893694 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL14560557 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1
SCHEMBL9625295 0.92 HEXA (0.69) HEXAHEXBSIRT1CYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US claimed
EP-0210851-B1 Mixtures of polyamideimides, containing 3,4'-diaminodiphenylether as diamine component, and of a plasticizer. TEIJIN LIMITED (JP) 1992-03-18 EP disclosed
EP-0156966-B1 WHOLLY AROMATIC POLYESTER COMPOSITION AND PROCESS FOR PRODUCING IT TEIJIN LIMITED (JP) 1988-10-19 EP disclosed
EP-0070539-B1 PROCESS FOR PRODUCING A FILM-LIKE AND FIBROUS ARTICLE OF A WHOLLY AROMATIC POLYESTER TEIJIN LIMITED (JP) 1987-07-01 EP disclosed
EP-0091669-B1 PROCESS FOR PRODUCING POROUS, FILM-LIKE OR FIBROUS STRUCTURE OF AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-10-01 EP disclosed
EP-0057387-B1 PRODUCTION OF A FILM-LIKE OR FIBROUS STRUCTURE OF AN AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-05-07 EP disclosed
EP-0156966-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1985-10-09 EP disclosed
US-4517315-A Production of a film-like or fibrous structure of an aromatic polyester TEIJIN LIMITED (JP) 1985-05-14 US disclosed
US-4419308-A SOLVENT EXTRACTION OF IMIDE OR ISOCYANURATE TEIJIN LIMITED (JP) 1983-12-06 US disclosed
US-4416839-A Wholly aromatic polyester composition, process for production thereof, and production therefrom of a film-like or fibrous article of a wholly aromatic polyester TEIJIN LIMITED (JP) 1983-11-22 US disclosed
EP-0091669-A2 Process for producing porous, film-like or fibrous structure of aromatic polyester TEIJIN LIMITED (JP) 1983-10-19 EP disclosed