Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469584 | 0.80 | AR (0.61) | ARCYP11B2CYP19A1NSD2 | |
| SCHEMBL6468889 | 0.79 | AR (0.86) | ARCYP11B2CYP19A1KDM4EALDH1A1 | |
| SCHEMBL6465872 | 0.79 | AR (0.76) | ARCYP11B2CYP19A1CNR1 | |
| SCHEMBL5365931 | 0.78 | AR (0.65) | ARCYP11B2KCNH2CNR1 | |
| SCHEMBL6466724 | 0.78 | AR (0.58) | ARCYP11B2CYP19A1GRIA2GRIA4 | |
| SCHEMBL6468342 | 0.78 | AR (0.58) | ARCYP11B2CYP19A1 | |
| SCHEMBL6466150 | 0.76 | AR (0.69) | ARCYP11B2CYP19A1KDM4EALDH1A1 | |
| SCHEMBL5366353 | 0.76 | AR (0.60) | ARCYP11B2KCNH2GRIA2GRIA4 | |
| SCHEMBL24414502 | 0.76 | AR (0.80) | ARCYP11B2CYP19A1ALDH1A1CNR1 | |
| SCHEMBL5365605 | 0.76 | AR (0.56) | ARCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |