Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14348165 | 0.90 | AR (0.48) | ARCYP11B2KDM1AGRIA2GRIA4 | |
| SCHEMBL5369671 | 0.80 | AR (0.60) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL6466733 | 0.79 | AR (0.60) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL6466987 | 0.79 | AR (0.58) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL5362232 | 0.79 | AR (0.61) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL6468889 | 0.78 | AR (0.86) | ARCYP11B2 | |
| SCHEMBL5362087 | 0.78 | AR (0.60) | ARCYP11B2GRIA2GRIA4KCNH2 | |
| SCHEMBL6466150 | 0.78 | AR (0.69) | ARCYP11B2GRIN2B | |
| SCHEMBL5361772 | 0.77 | AR (0.53) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL5365931 | 0.77 | AR (0.65) | ARCYP11B2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |