SCHEMBL5357722

SCHEMBL5357722

CS(=O)(=O)Nc1ccc2[nH]cc(C3CCN(CC(=O)C4CCN(C(=O)C=Cc5ccc(F)c(F)c5F)CC4)CC3)c2c1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348753 0.91 CCR2 (0.73) CCR2
SCHEMBL5348755 0.91 CCR2 (0.73) CCR2
SCHEMBL5319307 0.85 CCR2 (0.83) CCR2
SCHEMBL5314347 0.84 CCR2 (0.83) CCR2
SCHEMBL14441204 0.83 CCR2 (0.62) CCR2
SCHEMBL5315432 0.79 CCR2 (0.74) CCR2
SCHEMBL5361697 0.78 CCR2 (0.78) CCR2
SCHEMBL5324408 0.78 CCR2 (0.78) CCR2
SCHEMBL5359755 0.78 CCR2 (0.77) CCR2
SCHEMBL5359747 0.78 CCR2 (0.77) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007130712-A1 SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES JANSSEN PHARMACEUTICA, NV (BE) 2007-11-15 WO disclosed