Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MARS1 | P56192 | 7/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092755 | 0.86 | CNR1 (0.52) | CNR1 | |
| SCHEMBL5363014 | 0.83 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL5358211 | 0.83 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4453192 | 0.82 | CNR1 (0.64) | CNR1SRD5A2MARS1 | |
| SCHEMBL4463174 | 0.82 | CNR1 (0.64) | CNR1SRD5A2MARS1 | |
| SCHEMBL5354418 | 0.79 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL5355366 | 0.79 | CNR1 (1.00) | CNR1 | |
| SCHEMBL4807383 | 0.79 | CNR1 (0.53) | CNR1SRD5A2MARS1CNR2 | |
| SCHEMBL5359856 | 0.78 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4781819 | 0.77 | MAP4K4 (0.59) | SRD5A2MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271266-B2 | Substituted 2,3-diphenyl pyridines | MERCK & CO., INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | MERCK SHARP & DOHME CORP. | 2005-08-18 | — | — | US | disclosed |
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084930-A1 | DIPHENYLPYRIDINE DERIVATIVES, THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2003-10-16 | — | — | WO | disclosed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | CNR1, CNR2, MAG | CNR1 1/4885SRD5A2 4833/4885MARS1 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.