Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | CDH1 | P12830 | 1/20 | 0.46 |
| ▸ | APC | P25054 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358199 | 0.86 | CNR1 (0.70) | CNR1 | |
| SCHEMBL2837730 | 0.84 | KDM4E (0.54) | CNR1CYP3A4CYP2C8CYP2C9DHODH | |
| SCHEMBL19835545 | 0.81 | SLC6A3 (0.51) | CNR1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL17142084 | 0.78 | MAP4K4 (0.44) | CNR1MAP4K4CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL17144259 | 0.76 | CNR2 (0.47) | CNR1CYP3A4CYP2C8CYP2C9DHODH | |
| SCHEMBL2704945 | 0.76 | CNR1 (0.67) | CNR1MAP4K4CDH1APCCTNNB1 | |
| SCHEMBL6080079 | 0.75 | KDM4E (0.45) | MAP4K4CYP3A4CYP2C8CYP2C9DHODH | |
| SCHEMBL15439892 | 0.75 | CDH1 (0.49) | CNR1DHODHCDH1APCCTNNB1 | |
| SCHEMBL3054637 | 0.74 | CNR2 (0.56) | CNR1KMOKDM4EALOX15TSHR | |
| SCHEMBL31301301 | 0.74 | CNR2 (0.56) | CNR1KMOKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084930-A1 | DIPHENYLPYRIDINE DERIVATIVES, THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2003-10-16 | — | — | WO | disclosed |