Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL148664 | 0.82 | — | — | |
| Fluoride SCHEMBL81457 | 0.82 | — | — | |
| Fluoride SCHEMBL5238901 | 0.82 | — | — | |
| Fluoride SCHEMBL7724825 | 0.82 | CA4 (0.50) | — | |
| Fluoride SCHEMBL20918134 | 0.82 | — | — | |
| Fluoride SCHEMBL25249859 | 0.82 | — | — | |
| Fluoride SCHEMBL6328976 | 0.82 | — | — | |
| Fluoride SCHEMBL37567 | 0.82 | — | — | |
| Fluoride SCHEMBL11537573 | 0.82 | — | — | |
| Iodide SCHEMBL9731841 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235593-B2 | Mixing in the absence of actinic radiation a triarylsulfonium, diaryliodonium, dialkylphenacylsulfonium or hydroxyphenyldialkylsulfonium photoinitiator with an oxetane or oxirane monomer/oligomer component and pre-irradiating to activate while controlling temperature to prevent spontaneous polymerization | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2007-06-26 | — | — | US | disclosed |
| EP-1651700-A1 | COMMAND-CURE ADHESIVES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20050092428-A1 | Command-cure adhesives | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2005-05-05 | — | — | US | disclosed |
| WO-2005016989-A1 | COMMAND-CURE ADHESIVES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2005-02-24 | — | — | WO | disclosed |