SCHEMBL5358465

SCHEMBL5358465

CCCCCCCCOc1ccc(C(=O)O)cc1F

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.68
THRB P10828 1/20 0.68
ALDH1A1 P00352 1/20 0.64
HPGD P15428 1/20 0.64
PTPN11 Q06124 2/20 0.63
PLA2G2D Q9UNK4 1/20 0.62
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
LMNA P02545 1/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 1/20 0.59
RAB9A P51151 1/20 0.59
PLA2G4B P0C869 1/20 0.59
PLA2G2A P14555 2/20 0.58
RARB P10826 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347089 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
SCHEMBL9437150 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
SCHEMBL15731804 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
SCHEMBL9440284 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
SCHEMBL8646009 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
SCHEMBL9440043 1.00 THRA (0.68) THRATHRBALDH1A1HPGDPTPN11
Hydrochloric Acid SCHEMBL9626607 0.98 THRA (0.67) THRATHRBALDH1A1HPGDPTPN11
Hydrochloric Acid SCHEMBL7523098 0.98 THRA (0.67) THRATHRBALDH1A1HPGDPTPN11
Hydrochloric Acid SCHEMBL9626644 0.98 THRA (0.67) THRATHRBALDH1A1HPGDPTPN11
Hydrochloric Acid SCHEMBL9627293 0.98 THRA (0.67) THRATHRBALDH1A1HPGDPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9059410-B2 Liquid crystalline organic semiconductor material and organic semiconductor device using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2015-06-16 US disclosed
US-20120283397-A1 STYRENE POLYMER AND MANUFACTURING METHOD THEREFOR NIPPON SODA CO., LTD. (JP) 2012-11-08 US disclosed
EP-2511309-A1 STYRENE POLYMER AND MANUFACTURING METHOD THEREFOR Nippon Soda Co., Ltd. (JP) 2012-10-17 EP disclosed
US-20080058544-A1 Liquid crystalline organic semiconductor material and organic semiconductor device using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-03-06 US disclosed
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0341686-B1 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORP (JP) 1994-08-17 EP disclosed
EP-0315193-B1 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH & TELEPHONE (JP) 1994-04-06 EP disclosed
EP-0357702-B1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK PATENT GmbH (DE) 1992-08-12 EP disclosed
US-5098602-A Aromatic ester derivatives and fluorophenol ketones NIPPON MINING CO., LTD. (JP) 1992-03-24 US disclosed
US-5059345-A Spontaneous polarization in wide temperature range and high speed response NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-22 US disclosed
EP-0357702-A1 FLUORINATED OLIGOPHENYL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-03-14 EP disclosed
EP-0341686-A2 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORPORATION (JP) 1989-11-15 EP disclosed
CN-1035107-A FLUORINATED OLIGOPHENYL DERIVATIVES MERCK PATENT GMBH (DE) 1989-08-30 CN disclosed
WO-1989006678-A1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed
EP-0315193-A2 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080058544-A1 Liquid crystalline organic semiconductor material and organic semiconductor device using same SLCO4C1, SLCO2A1, SLCO1A2 THRA 4509/4885THRB 4729/4885ALDH1A1 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.