Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719025 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL946588 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL3376695 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL16235771 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL983844 | 0.75 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL6837256 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL953967 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL1431096 | 0.75 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL10551288 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL16559320 | 0.73 | POLB (0.48) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |