SCHEMBL5359169

SCHEMBL5359169

CCCCC#CCCCCCCO

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
LMNA P02545 2/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
HSD17B10 Q99714 1/20 0.60
TSHR P16473 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.55
PTPN7 P35236 5/20 0.50
HMGCR P04035 3/20 0.50
RECQL P46063 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
BLM P54132 1/20 0.42
MCL1 Q07820 1/20 0.42
SELP P16109 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL562635 1.00 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL3190238 1.00 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL11850801 0.97 ALDH1A1 (0.57) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL12680241 0.97 SMN1; SMN2 (0.58) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL2802419 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL8027862 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL21411191 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL20991348 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL11065903 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL11129684 0.95 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160953-B2 Polymeric surface coatings BIOCOMPATIBLES UK LIMITED (GB) 2007-01-09 US disclosed
US-20040176556-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2004-09-09 US disclosed
EP-0861858-B1 Polymeric surface coatings BIOCOMPATIBLES UK LTD (GB) 2004-06-30 EP disclosed
US-6743878-B2 FOR IMPROVED BIOCOMPATIBILITY/HAEMOCOMPATIBILITY WITH LIVING TISSUES BIOCOMPATIBLES UK LIMITED (GB) 2004-06-01 US disclosed
US-20030190405-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2003-10-09 US disclosed
US-6395800-B1 BLEND OF 2-(METHACRYLOYLOXYETHYL)-2*-(TRIMETHYLAMMONIUM)ETHYL PHOSPHATE POLYMER; MEDICAL EQUIPMENT, CATHETERS; BIOCOMPATIBILITY BIOCOMPATIBLES LIMITED (GB) 2002-05-28 US disclosed
US-6225431-B1 COATING SURFACE OF MEDICAL DEVICE WITH POLYMER FORMED BY RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS DISPERSED OR DISSOLVED IN A SOLVENT AND THE SOLVENT IS REMOVED TO LEAVE A STABLE COATING ON SURFACE BIOCOMPATIBLES LIMITED 2001-05-01 US disclosed
US-6150432-A IMPROVING THE BIOCOMPATIBILITY OF A POLYMER, DISPERSION OF A POLYMER AND INCREASE LUBRICITY BY BLENDING WITH A ZWITTERIONIC POLYMER; A MEDICAL EQUIPMENT WITH REDUCING FIBRINOGEN ABSORPTION, PLATELET ACTIVATION BIOCOMPATIBLES LIMITED (GB) 2000-11-21 US disclosed
US-6090901-A Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 2000-07-18 US disclosed
US-6087462-A BONDING OF COATINGS TO SURFACES WITH ZWITTWRIONS BIOCOMPATIBLES LIMITED (GB) 2000-07-11 US disclosed
EP-0818479-A2 Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 1998-01-14 EP disclosed
US-5705583-A RENDERING SURFACES BIOCOMPATIBLE BIOCOMPATIBLES LIMITED (GB) 1998-01-06 US disclosed
EP-0810239-A2 Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 1997-12-03 EP disclosed
US-5648442-A ZWITTERIONIC POLYMERS BIOCOMPATIBLES LIMITED (GB) 1997-07-15 US disclosed
US-5492964-A HYDROGENATION CATALYSTS UNIVERSITY OF SOUTH CAROLINA (US) 1996-02-20 US disclosed
EP-0626983-A1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LIMITED (GB) 1994-12-07 EP disclosed
WO-1994014897-A1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LIMITED (GB) 1994-07-07 WO disclosed
EP-0593561-A1 POLYMERIC SURFACE COATINGS BIOCOMPATIBLES LIMITED (GB) 1994-04-27 EP disclosed
WO-1993001221-A1 POLYMERIC SURFACE COATINGS BIOCOMPATIBLES LIMITED (GB) 1993-01-21 WO disclosed
WO-1991014500-A1 CERAMIC MATERIALS, METHOD OF PREPARING THE SAME AND HYDROGENATION AND OXIDATION PROCESSES USING THE SAME UNIVERSITY OF SOUTH CAROLINA (US) 1991-10-03 WO disclosed