SCHEMBL5359243

SCHEMBL5359243

NCCCCC(N)(Cl)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.45
LMNA P02545 3/20 0.42
BLM P54132 3/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2D6 P10635 1/20 0.41
NFKB1 P19838 1/20 0.41
NPSR1 Q6W5P4 2/20 0.39
THRB P10828 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
PLG P00747 1/20 0.39
ALOX15 P16050 1/20 0.39
SLC6A2 P23975 1/20 0.39
RECQL P46063 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14860368 1.00 ODC1 (0.45) ODC1LMNABLMKDM4EMAPT
SCHEMBL7200787 0.78 ODC1 (0.42) ODC1LMNABLMKDM4EMAPT
SCHEMBL7200793 0.78 ODC1 (0.42) ODC1LMNABLMKDM4EMAPT
Hydrochloric Acid SCHEMBL11732448 0.77 BLM (0.47) ODC1LMNABLMKDM4EMAPT
SCHEMBL2587404 0.76 ODC1 (0.48) ODC1LMNABLMKDM4EMAPT
SCHEMBL2115160 0.76 ODC1 (0.48) ODC1LMNABLMKDM4EMAPT
SCHEMBL7196982 0.75 ODC1 (0.44) ODC1LMNABLMKDM4EMAPT
SCHEMBL7203424 0.75 ODC1 (0.44) ODC1LMNABLMKDM4EMAPT
SCHEMBL1512913 0.74 ODC1 (0.47) ODC1LMNABLMKDM4EMAPT
SCHEMBL29359936 0.74 ODC1 (0.63) ODC1LMNABLMKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2584037-B1 METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME RIKEN (JP) 2016-08-10 EP disclosed
US-9340790-B2 Method for constructing recombinant bacterium for producing non-native protein, and utilization of same RIKEN (JP) 2016-05-17 US disclosed
EP-2584037-A1 METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME Riken (JP) 2013-04-24 EP disclosed
US-20130095524-A1 METHOD FOR CONSTRUCTING RECOMBINANT BACTERIUM FOR PRODUCING NON-NATIVE PROTEIN, AND UTILIZATION OF SAME RIKEN (JP) 2013-04-18 US disclosed
US-7223833-B1 Peptide nucleic acid conjugates ISIS PHARMACEUTICALS, INC. (US) 2007-05-29 US disclosed
EP-0804456-B1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS INC (US) 2002-08-21 EP disclosed
EP-0804456-A4 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS INC (US) 1999-05-19 EP disclosed
EP-0804456-A1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS, INC. (US) 1997-11-05 EP disclosed
WO-1996011205-A9 PEPTIDE NUCLEIC ACID CONJUGATES 1996-05-30 WO disclosed
WO-1996011205-A1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS, INC. (US) 1996-04-18 WO disclosed