SCHEMBL2587404

SCHEMBL2587404

NCCCCC(N)(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.48
LMNA P02545 3/20 0.45
BLM P54132 3/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
PMP22 Q01453 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NFKB1 P19838 2/20 0.44
CYP2D6 P10635 1/20 0.44
NPSR1 Q6W5P4 2/20 0.42
THRB P10828 2/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PLG P00747 1/20 0.42
ALOX15 P16050 1/20 0.42
SLC6A2 P23975 1/20 0.42
RECQL P46063 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6632838 0.92 ODC1 (0.56) ODC1LMNABLMKDM4EMAPT
SCHEMBL2115160 0.80 ODC1 (0.48) ODC1LMNABLMKDM4EMAPT
SCHEMBL4854796 0.80 ARG2 (0.52) ODC1LMNABLMKDM4EMAPT
SCHEMBL1512916 0.78 ODC1 (0.47) ODC1LMNABLMKDM4EMAPT
SCHEMBL259016 0.78 FDPS (0.48) KMT2AMEN1ALDH1A1ALOX15FDPS
SCHEMBL29290 0.78 LMNA (0.52) LMNABLMPMP22NFKB1CYP2D6
SCHEMBL29359936 0.78 ODC1 (0.63) ODC1LMNABLMKDM4EMAPT
SCHEMBL15315407 0.78 PAOX (0.44) ODC1LMNABLMKDM4EMAPT
SCHEMBL3624118 0.78 ARG1 (0.35) ODC1LMNABLMPMP22THRB
SCHEMBL1512913 0.78 ODC1 (0.47) ODC1LMNABLMKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110632227-B Method for distinguishing Liuyang fermented soya beans, Yangjiang fermented soya beans and Yongchuan fermented soya beans 中南林业科技大学 2022-03-18 CN claimed
EP-4324882-A2 BINDERS Knauf Insulation SPRL (BE) 2024-02-21 EP disclosed
EP-3146010-B1 BINDERS KNAUF INSULATION INC (US) 2023-12-13 EP disclosed
CN-107530396-B Adiponectin peptidomimetics for the treatment of ophthalmic diseases 雅利斯塔制药公司 2022-08-26 CN disclosed
US-11332577-B2 Binders KNAUF INSULATION SPRL (BE) 2022-05-17 US disclosed
CN-112752575-A Use of histidine, glycine and other amino acids for the prevention of insulin resistance and/or diabetes 雀巢产品有限公司 2021-05-04 CN disclosed
CN-112740045-A Markers for the risk of developing insulin resistance in childhood and adolescence 雀巢产品有限公司 2021-04-30 CN disclosed
US-20190119446-A1 BINDERS KNAUF INSULATION, INC. 2019-04-25 US disclosed
US-20170174836-A1 BINDERS KNAUF INSULATION SPRL (BE) 2017-06-22 US disclosed
US-20170103184-A1 INJECTABLE FILLER NGUYEN PHI (US) 2017-04-13 US disclosed
EP-1188767-A1 Isolated antioxidant peptides from casein and methods for preparing, isolating and identifying antioxidant peptides KRAFT FOODS HOLDINGS, INC. (US) 2002-03-20 EP disclosed
EP-1180240-A1 PROCESS FOR UTILIZING EPITOPES RECOGNIZED BY NATURAL ANTIBODIES Mirus Corporation (US) 2002-02-20 EP disclosed
EP-0619732-B1 BIODEGRADABLE POLYMERS FOR CELL TRANSPLANTATION MASSACHUSETTS INST TECHNOLOGY (US) 2001-01-31 EP disclosed
US-6171577-B1 ACCESSIBLE SULFHYDRYL GROUP; AND HEXOSE MOIETY RECOGNIZED BY A MAMMALIAN LIVER RECEPTOR, WHEREIN THE HEXOSE MOIETY IS CONJUGATED TO THE ANNEXIN. NEORX CORPORATION 2001-01-09 US disclosed
WO-2000065350-A1 PROCESS FOR UTILIZING EPITOPES RECOGNIZED BY NATURAL ANTIBODIES MIRUS CORPORATION (US) 2000-11-02 WO disclosed
EP-1001978-A1 ANGIOTENSIN DERIVATIVES Proteus Molecular Design Limited (GB) 2000-05-24 EP disclosed
US-5968477-A IMAGING AGENTS WITH SULFHYDRYL GROUPS AND HEXOSE GROUPS NEORX CORPORATION (US) 1999-10-19 US disclosed
WO-1998058952-A1 ANGIOTENSIN DERIVATIVES PROTEUS MOLECULAR DESIGN LIMITED (GB) 1998-12-30 WO disclosed
US-5629427-A MICROBIOCIDE, ANTITUMOR PETERSON DWIGHT M (US) 1997-05-13 US disclosed
US-5399665-A Reacting an alpha-amino acid with an alpha-hydroxy acid to form a morpholinedione, polymerizing morpholinedione with Lewis acid; biologically active moieties may be coupled to the polymer MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1995-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170103184-A1 INJECTABLE FILLER MMP1, IDE, INHA ODC1 4260/4885LMNA 2343/4885BLM 2041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.