Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 11/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CDK11B | P21127 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.39 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.39 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357503 | 0.85 | ADORA1 (0.54) | ADORA1BRD4IKBKBCDK11BCDK7 | |
| SCHEMBL5357594 | 0.84 | BRD4 (0.48) | ADORA1BRD4 | |
| SCHEMBL5356548 | 0.84 | ADORA1 (0.47) | ADORA1BRD4IKBKBCDK11BCDK7 | |
| SCHEMBL5357433 | 0.83 | ADORA1 (0.53) | ADORA1BRD4IKBKBCDK11BCDK7 | |
| SCHEMBL5362434 | 0.83 | ADORA1 (0.77) | ADORA1BRD4 | |
| SCHEMBL5363335 | 0.82 | ADORA1 (0.51) | ADORA1BRD4 | |
| SCHEMBL5362701 | 0.82 | ADORA1 (0.75) | ADORA1BRD4 | |
| SCHEMBL5361972 | 0.82 | ADORA1 (0.53) | ADORA1BRD4IKBKB | |
| SCHEMBL5354444 | 0.81 | ALDH1A1 (0.51) | ADORA1BRD4 | |
| SCHEMBL5356547 | 0.80 | ADORA1 (0.54) | ADORA1BRD4IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202245-B2 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | CYP4B1, CYP3A4, CYP1B1 | ADORA1 12/4885BRD4 784/4885IKBKB 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.