Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355948 | 0.90 | AOC3 (0.49) | AOC3ABCC1SIRT2 | |
| SCHEMBL5360863 | 0.90 | AOC3 (0.48) | AOC3ABCC1SIRT2 | |
| SCHEMBL5358940 | 0.90 | AOC3 (0.48) | AOC3ABCC1SIRT2HCAR2 | |
| SCHEMBL5356017 | 0.89 | KMT2A (0.52) | AOC3ABCC1HCAR2 | |
| SCHEMBL5363526 | 0.86 | AOC3 (0.48) | AOC3ABCC1SIRT2HCAR2 | |
| SCHEMBL6251973 | 0.80 | ABCC1 (0.44) | ABCC1SIRT2HCAR2 | |
| SCHEMBL5365588 | 0.80 | ABCC1 (0.45) | AOC3ABCC1SIRT2HCAR2 | |
| SCHEMBL5365810 | 0.80 | AOC3 (0.48) | AOC3SIRT2 | |
| SCHEMBL5360728 | 0.80 | AOC3 (0.46) | AOC3 | |
| SCHEMBL6258293 | 0.78 | AOC3 (0.46) | AOC3SIRT2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307078-B2 | Polycyclic compounds which modulate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-12-11 | — | — | US | claimed |
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |