Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356017 | 0.81 | KMT2A (0.52) | AOC3HCAR2KMT2A | |
| SCHEMBL5363526 | 0.79 | AOC3 (0.48) | AOC3HCAR2SIRT2NPC1RAB9A | |
| SCHEMBL5355948 | 0.78 | AOC3 (0.49) | AOC3SIRT2 | |
| SCHEMBL5359635 | 0.78 | AOC3 (0.50) | AOC3HCAR2SIRT2 | |
| SCHEMBL5360863 | 0.78 | AOC3 (0.48) | AOC3SIRT2 | |
| SCHEMBL5358940 | 0.78 | AOC3 (0.48) | AOC3HCAR2SIRT2 | |
| SCHEMBL5361000 | 0.74 | HSD17B2 (0.54) | AOC3HCAR2SIRT2KMT2AHSD17B1 | |
| SCHEMBL5363528 | 0.73 | POLB (0.54) | AOC3SIRT2POLBKMT2AHSD17B1 | |
| SCHEMBL5359044 | 0.73 | AOC3 (0.43) | AOC3SIRT2KDM4EALDH1A1NPC1 | |
| SCHEMBL5365588 | 0.73 | ABCC1 (0.45) | AOC3HCAR2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |