Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.45 |
| ▸ | FNTA | P49354 | 6/20 | 0.41 |
| ▸ | FNTB | P49356 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365280 | 0.91 | AR (0.44) | ARFNTAFNTBMAPTTDP1 | |
| SCHEMBL5363993 | 0.81 | AR (0.46) | ARFNTAFNTBMAPTKDM4E | |
| SCHEMBL5360255 | 0.72 | CYP3A4 (0.38) | MAPTTDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL5359872 | 0.72 | CYP3A4 (0.38) | MAPTTDP1KDM4EGAASMN1; SMN2 | |
| SCHEMBL5359879 | 0.72 | AR (0.52) | ARFNTAFNTBMAPTTDP1 | |
| SCHEMBL5362481 | 0.70 | AR (0.52) | ARFNTAFNTBMAPTKDM4E | |
| SCHEMBL5357482 | 0.69 | CYP3A4 (0.40) | MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL4919701 | 0.69 | AR (0.59) | ARFNTAFNTBMAPTTDP1 | |
| SCHEMBL4911697 | 0.69 | AR (0.67) | ARFNTAFNTBMAPTTDP1 | |
| SCHEMBL5362977 | 0.68 | AR (0.48) | ARFNTAFNTBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |