Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.52 |
| ▸ | FNTA | P49354 | 4/20 | 0.44 |
| ▸ | FNTB | P49356 | 4/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373726 | 0.88 | AR (0.61) | ARFNTAFNTBALPL | |
| SCHEMBL14347697 | 0.81 | AR (0.53) | ARFNTAFNTBALPL | |
| SCHEMBL5362087 | 0.81 | AR (0.60) | AR | |
| SCHEMBL5359277 | 0.79 | AR (0.61) | ARFNTAFNTB | |
| SCHEMBL5362232 | 0.77 | AR (0.61) | ARFNTAFNTB | |
| SCHEMBL5937220 | 0.77 | ALPL (0.70) | ALPLMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5362481 | 0.76 | AR (0.52) | ARFNTAFNTBMAPTLMNA | |
| SCHEMBL5361524 | 0.76 | AR (0.54) | AR | |
| SCHEMBL4919701 | 0.75 | AR (0.59) | ARFNTAFNTBMAPTTDP1 | |
| SCHEMBL4911697 | 0.75 | AR (0.67) | ARFNTAFNTBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |