Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026091 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL156256 | 0.81 | NOTUM (0.82) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9392589 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL23752365 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL13525164 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL26763833 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL13524325 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL6127792 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL11710635 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL5356749 | 0.76 | MAPT (0.73) | KDM4EALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146230-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-12-21 | — | — | WO | claimed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |