Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27435845 | 0.80 | TSHR (0.37) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL846984 | 0.78 | EGLN1 (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL9543105 | 0.78 | — | — | |
| SCHEMBL27865301 | 0.78 | EGLN1 (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL10168232 | 0.77 | TSHR (0.55) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL21699936 | 0.77 | MAPT (0.65) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL1134609 | 0.76 | MAPT (0.58) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL19845084 | 0.76 | TSHR (0.49) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL19845081 | 0.76 | TSHR (0.49) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL1071857 | 0.76 | TSHR (0.49) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300739-B2 | Negative resists based on a acid-catalyzed elimination of polar molecules | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070026339-A1 | NEGATIVE RESISTS BASED ON A ACID-CATALYZED ELIMINATION OF POLAR MOLECULES | GLOBALFOUNDRIES U.S. INC. | 2007-02-01 | — | — | US | disclosed |